KRT8 anticorps

N° du produit ABIN2742508

Cet anticorps Souris Monoclonal détecte spécifiquement KRT8 dans WB, IHC, IF, FACS, ELISA, IHC (p) et IP. Il présente une réactivité envers Humain, Rat et Poisson zèbre (Danio rerio).

Aperçu rapide pour KRT8 anticorps (ABIN2742508)

Antigène: KRT8 (Keratin 8 (KRT8))

Reactivité: Humain, Rat, Poisson zèbre (Danio rerio)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KRT8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Clone: H1

Détail du produit anti-KRT8 anticorps

Specificité: Human KRT8 / CK8 / Cytokeratin 8

Purification: Protein G purified

Immunogène: A cytoskeleton preparation containing cytokeratin 8.

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA, Flo (0.5 - 1 μg/10 x10⁶), IF (1 - 2 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (1 - 2 μg/mL)

Usage: Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). Cytokeratin 8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibody that recognizes only cytokeratin 8 and 18. Cytokeratin 8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. antibody to Cytokeratin 8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against Cytokeratin 8, 18 and 19). Reportedly, Cytokeratin 8 antibody is useful for the differentiation of lobular ([Character 93]ring-like, perinuclear[Character 94]) from ductal ([Character 93]peripheral-predominant[Character 94]) carcinoma of the breast. ELISA: Order BSA-free format for coating.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2°C to 8°C.

Détails sur KRT8

Antigène: KRT8 (Keratin 8 (KRT8))

Autre désignation: KRT8 / CK8 / Cytokeratin 8

Sujet: Name/Gene ID: KRT8
Family: Keratin

Synonyms: KRT8, CARD2, CK-8, CYK8, Cytokeratin-8, CK8, K2C8, K8, KO, Keratin-8, Type-II keratin Kb8, Cytokeratin 8, Keratin 8

ID gène: 3856